The Donlin lab aims to increase understanding of the human immune system by analyzing patient samples with high-dimensional molecular and genomic technologies. Our projects are designed around clinical unmet needs in autoimmune and musculoskeletal disorders.
Ongoing projects include:
- Rheumatoid arthritis (RA) – molecular patterns and optimized treatment
- Immune checkpoint inhibitor arthritis (ICI-arthritis) – causes of autoimmune disease
- Autoimmune muscle disease
- Musculoskeletal tumors
Our multidisciplinary team based at the Hospital for Special Surgery (HSS) and Weill Cornell Medicine also participates in two consortia focused on mechanisms of disease: the NIH-industry sponsored Accelerating Medicines Partnership (AMP) and the NIHGRI Impact of Genomic Variation on Function (IGVF).