News | Graduate School of Medical Sciences

Researchers Unveil a Powerful New Gene-Switch Tool

Investigators at Weill Cornell Medicine have developed a versatile and non-toxic technology for controlling the activity of any gene in a cell. Such “gene-switch” tools allow scientists to “turn on” or “turn off” a target gene to study how it works, model diseases and design new therapies. The tool potentially could be adopted throughout biomedical research, including in the development of gene therapies.

Dr. Samie Jaffrey

NIH Awards $10 Million for the New York Regional Diabetes Research Center

New York, NY (October 23, 2025) Albert Einstein College of Medicine has received a five-year, $10.8 million grant from the National Institutes of Health (NIH) to create the New York Regional Diabetes Research Center (NYR-DRC), a newly expanded multi-institutional center co-led with the Icahn School of Medicine at Mount Sinai and Weill Cornell Medicine. The center will focus on discovering scientific knowledge and translating it into improved care for people with diabetes and related...

Galvanizing Blood Vessel Cells to Expand for Organ Transplantation

Scientists have discovered a method to induce human endothelial cells from a small biopsy sample to multiply in the laboratory, producing more than enough cells to replace damaged blood vessels or nourish organs for transplantation, according to a preclinical study by Weill Cornell Medicine investigators. Endothelial cells form the inner lining of blood vessels and regulate blood flow, inflammation and healing. Traditional approaches for growing these cells in the lab have yielded only...

colored dots representing individual cells

Cancer Progression Illuminated by New Multi-Omics Tool

A new tool developed by Weill Cornell Medicine and the University of Adelaide investigators has enhanced the ability to track multiple gene mutations while simultaneously recording gene activity in individual cancer cells. The technology, which can now use diverse types of pathology samples and quickly process large numbers of cells, has enabled the investigators to glean new insights into how cancers evolve toward greater aggressiveness and therapy resistance.

Dr...

Study Finds Restoring Order to Dividing Cancer Cells May Prevent Metastasis

Triple negative breast cancer (TNBC) is one of the most aggressive and hardest to treat breast cancers, but a new study led by Weill Cornell Medicine suggests a way to stop it from spreading. Researchers have discovered that an enzyme called EZH2 drives TNBC cells to divide abnormally, which enables them to relocate to distant organs. The preclinical study also found drugs that block EZH2 could restore order to dividing cells and thwart the spread of TNBC cells.

“Metastasis is the main...

drawing of brain with spots indicating activity

NIH Grant Will Fund Autism Research Replication, Validation, and Reproducibility Center

Investigators at Weill Cornell Medicine and Cornell’s Ithaca campus have received a $5.1 million, three-year grant from the National Institutes of Health’s Autism Data Science Initiative (ADSI) to launch the Autism Replication, Validation, and Reproducibility (AR²) Center. The center aims to improve the reliability of autism research and foster public trust in the field.

Dr. Judy Zhong

immunofluorescent image of cells stained green, red, and blue

NIH Funds Study of Type 1 Diabetes Development

Weill Cornell Medicine has received a four-year, $3.4 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health, for a study of the details and dynamics of the autoimmune process that causes type 1 diabetes. Dr. Shuibing Chen, the Kilts Family Professor of Surgery and director of the Center for Genomic Health at Weill Cornell Medicine, will lead the project. Dr. Chen’s long-time collaborator, Dr. Stephen Parker,...

Inflammation During Pregnancy May Prime Offspring for Anxiety

Increased risk for anxiety may begin before birth, shaped by infection or stressful events during pregnancy, according to a new preclinical study from researchers at Weill Cornell Medicine. While scientists have long known that maternal difficulty during pregnancy may raise a child’s risk for psychiatric illness, the biological pathways between these prenatal experiences and later mental health have been unclear.

The study, published Sept. 10 in Cell Reports, focuses on a region of the...

a woman sitting in front of a computer with a man looking over her shoulder

Weill Cornell Doctoral Student Selected for HHMI Fellows Program

Weill Cornell Graduate School of Medical Sciences doctoral student Ana Campos Codo has been selected for the 2025 cohort of the Gilliam Fellows Program by Howard Hughes Medical Institute (HHMI).

Codo, a student in the Immunology and Microbial Pathogenesis Ph.D. program, is one of 30 graduate students representing 23 different institutions across the United States who were chosen this year. The 21-year-old Gilliam Fellows program, which launches...

The Quest for an HIV Vaccine

When SARS-CoV-2, the coronavirus that causes COVID-19, began spreading worldwide in 2020, many research teams immediately set to work developing a vaccine against it. Building on decades of previous work on mRNA technology and on other viral vaccines, including HIV, they achieved their goal within the year. The most widely used mRNA vaccine design contains the genetic instructions for the body to make the spike protein that the virus uses to enter cells. The resulting immune response...

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