News | Graduate School of Medical Sciences

Burnout May Lead Family Doctors to Leave Medicine

Family physicians who report feeling burned out are nearly 1.5 times more likely to change practices or stop practicing medicine entirely compared to their peers who don’t report burnout, a study by Weill Cornell Medicine researchers found. Physician burnout can include emotional exhaustion, detachment from patients and colleagues, and feeling that work is no longer meaningful.

The findings, published March 30 in JAMA Internal Medicine, also highlight the consequences for patients:...

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Prostate Cancer Foundation Awards Grants to Weill Cornell Medicine Investigators

Six researchers from Weill Cornell Medicine have received Young Investigator Awards from the Prostate Cancer Foundation. These three-year grants award $225,000 to postdoctoral fellows and early-career faculty, helping to energize the field with fresh ideas. The Weill Cornell investigators are part of thirty-one researchers overall who were selected for the PCF’s Class of 2025 Young Investigators. The awardees will investigate how the disease occurs at a molecular level, search for new...

AI Tool Shows Promise in Diagnosing Advanced Heart Failure

Applying artificial intelligence techniques to cardiac ultrasound data may make it easier to identify patients with advanced heart failure, a new study has found. The study—led by investigators at Weill Cornell Medicine, Cornell Tech, Cornell Ann S. Bowers College of Computing and Information Science, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian—offers the prospect of better care for many thousands of patients who may be overlooked due to the...

little boy in bed with parents hand on head checking for fever

How One Flu Virus Can Hamper the Immune Response to Another

Prior exposure to one strain of influenza virus may weaken children’s ability to mount an effective antibody response against their subsequent exposure to a different flu strain, according to a study led by Weill Cornell Medicine investigators. The analysis of the pediatric response to H3N2 and H1N1 influenza A viruses, two of the most common causes of flu, provides insight into the concept of “immune imprinting,” and supports the idea that childhood vaccination, if...

Study Identifies Gene Linked to Chemotherapy Resistance in Prostate Cancer

A gene called FOXJ1 may drive resistance to taxane chemotherapy during treatment for advanced prostate cancer, according to a new study led by investigators at Weill Cornell Medicine and Beth Israel Deaconess Medical Center. The findings provide important new insights into why patients with metastatic disease often stop responding to a key class of life-prolonging chemotherapy drugs after initially benefiting. Given that taxanes remain the only chemotherapy agents with demonstrated survival...

Prior Authorization Bans for Buprenorphine Alone May Not Improve Treatment Retention

State laws that ban insurance prior authorization for buprenorphine—a leading medication for opioid use disorder—may not help more patients stay in treatment for the recommended minimum of 180 days, Weill Cornell Medicine researchers report. Though prescription buprenorphine can be a life-saving treatment that relieves opioid cravings and withdrawal symptoms, adherence to the medication is low.

Published March 6 in JAMA Health Forum, the study examined whether state laws prohibiting...

pregnant woman having blood pressure taken

New Model May Predict Preeclampsia in Late Pregnancy

A machine-learning model developed by Weill Cornell Medicine investigators may provide clinicians with an early warning of a complication that can occur late in pregnancy.

Weill Cornell Medicine Selected for Prostate Cancer Foundation Challenge Award

Dr. Ekta Khurana, an associate professor of systems and computational biomedicine at Weill Cornell Medicine, has received a two-year, $1 million Challenge Award from the Prostate Cancer Foundation to work with researchers from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center on an AI-based method for early detection of treatment-resistant prostate tumor subtypes.

Dr. Ekta Khurana

New Strategies Aim at HIV’s Last Strongholds

A new study has overcome a long-standing challenge—how to isolate and study elusive HIV-infected cells called authentic reservoir clones (ARCs) that evade the immune system, making the disease difficult to cure. Researchers from Weill Cornell Medicine, Rockefeller University, and collaborating institutions offer a unprecedented look into these hidden HIV‑harboring cells and show that some may be more vulnerable to immune destruction than previously believed.

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Triggering Self-Combustion in Fat Cells for Weight Loss

Ordinary fat cells in obese animals can be induced to burn energy stores, generating substantial heat, according to a preclinical study by Weill Cornell Medicine investigators.

In the study, published Feb. 23 in Nature Metabolism, the researchers showed that in fat cells called white adipocytes, high levels of fatty acids from fat stores, in the presence of a key enzyme called AAC, can trigger a process that uses fat to produce heat and increase energy expenditure. They demonstrated...

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