Research
Our laboratory analyzes large-scale observational datasets from electronic health records, health insurance claims, national surveys, social determinants of health, and social media platforms to study risk factors and treatment outcomes for mental illness and substance use disorders in adults and youths.
Current Projects
- Prediction of risk of suicidal thoughts and behaviors, postpartum depression, and drug overdose deaths
- Ascertainment of subtypes for treatment resistant depression
- Disparities in pregnancy associated medications for opioid use disorder
- Healthcare utilization in individuals with a serious mental illness
Bio
Dr. Pathak is the Frances & John L. Loeb Professor of Medical Informatics, chief of the Division of Health Informatics, and vice hhair for entrepreneurship in the Department of Population Health Sciences. His research focuses on the secondary use of electronic health records, insurance claims, and social determinants of health data to study mental and behavioral health outcomes in depression, substance use, and suicide. This work has been funded by the U.S. National Institutes of Health, the Veterans Health Administration, the Patient Centered Outcomes Research Institute, the Agency of Healthcare Research and Quality, the American Foundation for Suicide Prevention, Merck Pharmaceuticals, and several private foundations. Dr. Pathak has published over 250 papers, including book chapters and invited reviews. He is also the founder of Iris OB Health Inc. – a mental health startup spun out of Cornell, developing AI-based tools for the early detection of postpartum depression and anxiety. Dr. Pathak is a Fellow of the American College of Medical Informatics.
Distinctions:
- Fellow, American College of Medical Informatics (ACMI)
Selected Publications:
Xiao Y, Bi K, Yip PF, Cerel J, Brown TT, Peng Y, Pathak J, Mann JJ. Decoding Suicide Decedent Profiles and Signs of Suicidal Intent using Latent Class Analysis. JAMA Psychiatry, 2024. Accepted. In press.
Xi W, Banerjee S, Olfson M, Simon G, Alexopoulos GS, Zima B, Pathak J. Effects of Geography on Risk for Future Suicidal Ideation and Attempts among Children and Youth. Journal of American Academy of Child and Adolescent Psychiatry (JAACAP) Open, 2023. Accepted. In press.
Adekkanattu P, Olfson M, Coombes B, Fennessy B, Ryu E, Wickramaratne P, Weissman MM, Mann JJ, Charney AW, Biernacka JM, Pathak J. Comorbidity and Healthcare Utilization in Patients with Treatment Resistant Depression: A Large Scale Retrospective Cohort Analysis Using Electronic Health Records. Journal of Affective Disorders, 2023; 324(1): 102-113. PMID: 36529406
Xiao Y, Mann JJ, Pathak J, Yip P. Impact of Pandemic-Related Stressors and Vaccination on Trajectories of Child Mental Health during COVID-19 in the U.S.: Findings from the Longitudinal Adolescent Brain Cognitive Development (ABCD) Study. JAMA Psychiatry, 2022; 79(6):610-621. doi: 10.1001/jamapsychiatry.2022.0818. PMID: 35475851.
Zhang Y, Wang S, Hermann A, Reading Turchioe M, Pathak J. Development and Validation of a Machine Learning Algorithm for Risk of Postpartum Depression among Pregnant Women. Journal of Affective Disorders, 2021; 279(1):1-8; PMID: 33035748.