Applying artificial intelligence techniques to cardiac ultrasound data may make it easier to identify patients with advanced heart failure, a new study has found. The study—led by investigators at Weill Cornell Medicine, Cornell Tech, Cornell Ann S. Bowers College of Computing and Information Science, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian—offers the prospect of better care for many thousands of patients who may be overlooked due to the difficulty of diagnosing their condition.

Prior exposure to one strain of influenza virus may weaken children’s ability to mount an effective antibody response against their subsequent exposure to a different flu strain, according to a study led by Weill Cornell Medicine investigators. The analysis of the pediatric response to H3N2 and H1N1 influenza A viruses, two of the most common causes of flu, provides insight into the concept of “immune imprinting,” and supports the idea that childhood vaccination, if properly designed, may be able to mitigate its adverse effects.

A gene called FOXJ1 may drive resistance to taxane chemotherapy during treatment for advanced prostate cancer, according to a new study led by investigators at Weill Cornell Medicine and Beth Israel Deaconess Medical Center. The findings provide important new insights into why patients with metastatic disease often stop responding to a key class of life-prolonging chemotherapy drugs after initially benefiting.

A machine-learning model developed by Weill Cornell Medicine investigators may provide clinicians with an early warning of a complication that can occur late in pregnancy.

State laws that ban insurance prior authorization for buprenorphine—a leading medication for opioid use disorder—may not help more patients stay in treatment for the recommended minimum of 180 days, Weill Cornell Medicine researchers report. Though prescription buprenorphine can be a life-saving treatment that relieves opioid cravings and withdrawal symptoms, adherence to the medication is low.

Dr. Ekta Khurana, an associate professor of systems and computational biomedicine at Weill Cornell Medicine, has received a two-year, $1 million Challenge Award from the Prostate Cancer Foundation to work with researchers from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center on an AI-based method for early detection of treatment-resistant prostate tumor subtypes.

A new study has overcome a long-standing challenge—how to isolate and study elusive HIV-infected cells called authentic reservoir clones (ARCs) that evade the immune system, making the disease difficult to cure. Researchers from Weill Cornell Medicine, Rockefeller University, and collaborating institutions offer a unprecedented look into these hidden HIV‑harboring cells and show that some may be more vulnerable to immune destruction than previously believed.

Ordinary fat cells in obese animals can be induced to burn energy stores, generating substantial heat, according to a preclinical study by Weill Cornell Medicine investigators.