Graduate School of Medical Sciences
A partnership with the Sloan Kettering Institute

Extreme Risk Protection Order Laws Reduce Firearm Suicides

A new study found that laws temporarily restricting access to firearms for individuals at high risk of harming themselves or others reduced firearm suicides without a shift to other suicide methods, according to researchers at Weill Cornell Medicine and UC Berkeley School of Public Health.

Gut Bacteria May Tip the Balance between Feeding Tumors and Fueling Immunity

A new study reveals how bacteria in the gut can help determine whether the amino acid asparagine from the diet will feed tumor growth or activate immune cells against the cancer​, according to researchers at Weill Cornell Medicine. This casts the gut microbiome—the trillions of microorganisms living in the intestine—as a central player in the body's response to cancer and to modern cancer treatments like immunotherapies.

Weill Cornell Medicine Receives Funding to Develop Diagnostic Toolbox for Lymphatic Disease

Weill Cornell Medicine has received a $5.2 million, initial two-year award  from the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics, and pHenotyping Technologies (LIGHT) program to develop a comprehensive and innovative approach to diagnosing lymphatic disease. LIGHT is led by ARPA-H Program Manager Kimberley Steele, M.D., Ph.D.

Americans View Opioid Overdose as a Crisis that Needs to Be Addressed

Approximately 88% of adults view opioid overdose deaths as a very serious problem with high agreement across political groups, according to a national survey conducted by Weill Cornell Medicine researchers. However, political differences over who is responsible will shape the country’s next phase of drug policy.

Scientists Identify Pre-Cancerous States in Seemingly Normal Aging Tissues

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the first time, in a study led by investigators at Weill Cornell Medicine and the New York Genome Center.

Pain-Sensing Neurons Kick-Start Immune Responses

Pain-sensing neurons in the gut kindle inflammatory immune responses that cause allergies and asthma, according to a new study by Weill Cornell Medicine. The findings, published Jan. 7 in Nature, suggest that current drugs may not be as effective because they only address the immune component of these conditions, overlooking the contribution of neurons.

B Cells Transiently Unlock Their Plasticity, Risking Lymphoma Development

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During their preparation for this battle, B cells transiently revert to a more flexible, or plastic, stem-cell-like state in the lymph nodes, according to a new preclinical study from Weill Cornell Medicine investigators. The results could help explain how many lymphomas develop from mature B cells rather than from stem cells, as many other cancers do, and guide researchers in developing better treatments. 

Microbiome May Aid in Successful Pregnancies

Gut microbes may play a key role in training a mother’s immune system to adapt to the developing fetus during pregnancy, according to a preclinical study by Weill Cornell Medicine investigators.

Research Matters: How Folate Deficiency May Alter Genes to Promote Cancer

Students Break Down Big Science into Inspiring Stories

Three minutes and one slide were all it took for twelve young scientists to turn cutting-edge research into dramatic stories of hope at Weill Cornell Medicine’s tenth annual Three-Minute Thesis (3MT) competition on Nov. 13 in Uris Auditorium. The night showcased bold ideas about tackling Alzheimer’s disease, cancer, infectious diseases and more with creativity and passion.