NMR

NMR is an essential component of structural biology since it is uniquely suited to examine changes in the conformation, structure and mobility of biomolecules using solution conditions closely approximating the biological environment.  NMR is critical for chemical analysis and synthetic chemistry, providing atomic “eyesight” for confirming chemical compounds; NMR data is often required for patents and publications.  NMR is also a necessary component in drug discovery efforts.  Basic NMR applications can be employed for assessing sample purity, chemical changes, binding events and the effects of mutations.  More involved multidimensional NMR applications can be implemented for protein structure determination and dynamics investigations.    

The WCM Nuclear Magnetic Resonance (NMR) Core Facility provides state-of-the-art biological and chemical NMR resources, and expertise in their analytical, structural and biochemical applications, to the Weill Cornell Medicine (WCM) community and to outside investigators. Services include training in sample preparation, NMR data collection and data analysis. The core facility provides consultation on project design and data analysis, and offers seminars and training.

Core Director:

W. Clay Bracken, Ph.D.
Associate Professor of Research, Biochemistry
(212) 746-6473
wcb2001@med.cornell.edu

For more information about services and pricing, to register as a user of the core, to submit samples, to schedule time on the instruments, and/or to arrange for training, please go to the WCM iLab portal.