The goal of the Signal Transduction Module is to provide students with an understanding of the basic recurring themes in cell signaling mechanisms and to familiarize the students with a majority of the key signal transduction pathways. The course comprises approximately 30 lectures, each 1.5 hours in length. An emphasis is placed on: 1) the use of pharmacologic and chemical tools to study problems in signal transduction; and 2) structural insights into signaling mechanisms based on x-ray, NMR and computational approaches. By the end of the course students feel comfortable reading and comprehending journal articles related to the latest findings in signal transduction.