An introduction to the fundamentals of biostatistics with primary emphasis on understanding of statistical concepts behind data analytic principles. This course will also teach R, a freely available software, to explore, visualize and perform statistical analysis with data. Lectures and discussions will focus on the following: exploratory data analysis; basic concepts of statistics; construction of hypothesis tests and confidence intervals; the development of statistical methods for analyzing data; and development of mathematical models used to relate a response variable to explanatory or descriptive variables.