My research explores the use of information systems to promote communication and collaboration in patient care and biomedical research. The goal is to develop models that increase our understanding of interactions between information systems and biomedical organizational structures, patterns of work flow, and the specialized languages that professionals employ. This work is a fusion between technical and social disciplines, drawing from computer science, information technology, cognition, linguistics, behavioral and organizational science. Methods include natural language processing, linguistic analysis, content analysis, data modeling, work flow analysis and social network analysis. Applications include electronic health records, research databases, clinical research systems and systems to promote scientific collaboration.