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A common variation in a human gene that affects the brain’s reward processing circuit increases vulnerability to the rewarding effects of the main psychoactive ingredient of cannabis in adolescent females, but not males, according to preclinical research by Weill Cornell Medicine investigators. As adolescence represents a highly sensitive period of brain development with the highest risk for initiating cannabis use, these findings in mice have important implications for understanding the...

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The scope of the DNA changes that drive cancers has been illuminated as never before in a set of studies by a large international scientific team including Weill Cornell Medicine researchers.

In six studies published Feb. 5 in Nature, and 18 papers in other Nature-affiliated journals, this scientific consortium reported the results from analyses of DNA from more than 2,600 biopsied tumor samples across 38 different types of cancer. Unlike traditional cancer genetics projects that...

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Immune cell activity in the brain differs between males and females in ways that may explain why some neurodegenerative diseases affect the sexes differently, according to a new study from Weill Cornell Medicine scientists.

The study, published Dec. 23 in Nature Neuroscience, compared brain-resident immune cells called microglia in male and female mice. Microglia in Alzheimer’s disease and other neurodegenerative disorders appear to help protect the brain from the disease process,...

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Immune cell activity in the brain differs between males and females in ways that may explain why some neurodegenerative diseases affect the sexes differently, according to a new study from Weill Cornell Medicine scientists.

The study, published Dec. 23 in Nature Neuroscience, compared brain-resident immune cells called microglia in male and female mice. Microglia in Alzheimer’s disease and other neurodegenerative disorders appear to help protect the brain from the disease process,...

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Molecules that coordinate the development of highly specialized blood vessels in the kidney have been identified by investigators at Weill Cornell Medicine, University of Texas Southwestern Medical Center and Hofstra University. The findings pave the way toward new strategies for repairing damaged organs.

Dr. Shahin Rafii, director of Ansary Stem Cell Institute at Weill Cornell Medicine, and his colleagues performed a comprehensive analysis of the genetic programs that underlie the...

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Dr. Katherine Hajjar, an esteemed physician-scientist with expertise in pediatric hematology and vascular cell biology, has been named senior associate dean for faculty at Weill Cornell Medicine, effective Jan. 1. Dr. Judy Tung, a distinguished internist and educator, has been appointed associate dean for faculty development.

Dr. Hajjar will lead Weill Cornell Medicine’s Office of Faculty, which will focus on all aspects of faculty advancement at the institution and under whose...

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An inexpensive program using trained community members to deliver a structured program based on cognitive behavioral therapy by telephone was able to improve daily functioning, self-reported physical activity, and overall quality of life among diabetic patients with chronic pain, according to a clinical trial led by investigators at Weill Cornell Medicine, the University of Wisconsin-Madison and the University of Alabama at Birmingham.

The study, reported Jan. 13 in Annals of Family...

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BROOKLYN, NY (January 7, 2020) — Dr. Tan A. Ince has been named chief of pathology at NewYork-Presbyterian Brooklyn Methodist Hospital, effective February 1. Dr. Ince was also recruited to Weill Cornell Medicine as a professor of pathology and laboratory medicine.  

Dr. Ince will lead NewYork-Presbyterian Brooklyn Methodist’s pathology enterprise, which provides cutting-edge clinical and laboratory services and engages in translational research.  He also plans to build a biospecimen...

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Weill Cornell Medicine scientists have built the first global database of clinical trials testing a rapidly expanding approach to cancer treatment that involves genetically modifying immune cells to recognize specific targets on a patient’s cancer cells and attack them. By analyzing the approach, called chimeric antigen receptor (CAR) therapies, the scientists designed a “therapeutic roadmap” that identifies all current therapies as well as additional cancers that can be treated with them....

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The protein adipsin, which is produced in body fat, helps protect insulin-secreting cells called pancreatic beta cells from destruction in type 2 diabetes, according to a new study by researchers at Weill Cornell Medicine and NewYork-Presbyterian. Among middle-aged adults, higher levels of the protein in the blood were also associated with protection from type 2 diabetes.

The study, published Nov. 7 in Nature Medicine, may have implications for the future development of type 2 diabetes...

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