BCMB Students: 2012 Entering Class

Thesis Lab:

Mary Baylies

Undergraduate University: Vellore Institute of Technology

Publications:

• Imaging Approaches to Investigate Myonuclear Positioning in Drosophila.

Thesis Lab:

Iestyn Whitehouse

Undergraduate University: Moravian College

Publications:

• DNA replication through a chromatin environment.
• Spatiotemporal coupling and decoupling of gene transcription with DNA replication origins during embryogenesis in C. elegans.

Thesis Lab:

Xiaolan Zhao

Undergraduate University: University of North Carolina-Chapel Hill

Publications:

• Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates.
• Replication-associated recombinational repair: Lessons from budding yeast.
• Selective modulation of the functions of a conserved DNA motor by a histone fold complex.
• Restriction of replication fork regression activities by a conserved SMC complex.

Thesis Lab:

Ping Chi

Undergraduate University: Peking University

Publications:

• Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth

Thesis Lab:

Cole Haynes

Undergraduate Unversity: Tsinghua University

Publications:

• Mitochondrial and nuclear accumulation of the transcription factor ATFS-1 promotes OXPHOS recovery during the UPR
• The mitokine quest(ion)
• Mitochondrial dysfunction in cancer

Thesis Lab:

Sarat Chandarlapaty

Undergraduate University: University of Pune

Publication:

• Multi-organ Site Metastatic Reactivation Mediated by Non-canonical Discoidin Domain Receptor 1 Signaling

Thesis Lab:

Philipp Niethammer

Undergraduate University: Nankai University

Publication:

• Illuminating Phagocyte Biology

Thesis Lab:

Eric Lai

Undergraduate University: Harvard University

Publications:

• Alteration of miRNA activity via context-specific modifications of Argonaute proteins
• Intertwined pathways for Argonaute-mediated microRNA biogenesis in Drosophila
• Multiple In Vivo Biological Processes Are Mediated by Functionally Redundant Activities of Drosophila mir-279 and mir-996
• Age- and pregnancy-associated DNA methylation changes in mammary epithelial cells
• Selective Suppression of the Splicing-Mediated MicroRNA Pathway by the Terminal Uridyltransferase Tailor
• Dual Strategies for Argonaute2-Mediated Biogenesis of Erythroid miRNAs Underlie Conserved Requirements for Slicing in Mammals

Thesis Lab:

Richard Kolesnick

Undergraduate University: Boston University

Publication:

• Epigenetic regulation of hematopoietic stem cell development

Thesis Lab:

Eric Lai

Undergraduate University: National Taiwan University

Publications:

•  Selective Suppression of the Splicing-Mediated MicroRNA Pathway by the Terminal Uridyltransferase Tailor
• The m6A pathway facilitates sex determination in Drosophila
• Characterization of a TUTase/RNase complex required for Drosophila gametogenesis

Thesis Lab:

Scott Keeney

Undergraduate University: University of Colorado Boulder

Thesis Lab:

Neal Rosen

Undergraduate University: K.C. College, Mumbai University

Thesis Lab:

Todd Evans

Undergraduate University: Harvard University

Publication:

• Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
• ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression
• Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo
• Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms
• Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia
• Dnmt3a regulates myeloproliferation and liver-specific expansion of hematopoietic stem and progenitor cells
• The ceramide synthase 2b gene mediates genomic sensing and regulation of sphingosine levels during zebrafish embryogenesis

Thesis Lab:

Mary Goll

Undergraduate University: BITS-Pilani-Int.

Thesis Lab:

Heidi Stulhmann

Undergraduate University: R.V. College of Engineering

Publications:

• Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease
• Enhanced mitochondrial biogenesis ameliorates disease phenotype in a full-length mouse model of Huntington's disease

Thesis Lab:

Alexandra Joyner

Undergraduate University: University of California

Publication:

• Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins

Thesis Lab:

Stewart Shuman

Undergraduate University: University of California

Thesis Lab:

Scott Armstrong

Undergraduate University: Tsinghua University

Publication:

• The role of DOT1L in the maintenance of leukemia gene expression

Thesis Lab:

Richard White

Undergraduate University: Sichuan University

Publication:

• Reproducibility of quantitative susceptibility mapping in the brain at two field strengths from two vendors