Bio
The projects of this laboratory aim to provide new chemical genetic tools to define, perturb and manipulate essential functions of protein methyltransferases. Another focus in this laboratory is to design and synthesize tight-binding inhibitors as anti-cancer drug candidates by blocking these protein-modifying activities. Researchers in the field of chemistry, biology and biochemistry work together closely to synthesize novel chemical reagents, elucidate illness-causing mechanisms at molecular level and develop potential treatments for human diseases.