The Wendel lab pursues disease-centered and basic discovery research in cancer. Our disease focus is on the genetic pathogenesis of deadly forms of B cell malignancies. Our basic discovery work explores aberrant mRNA translation programs across different cancers.
The overarching goal of our work in both areas is to translate new insight into cancer genetics and biology into future therapies.
Work in the lab includes the full range of molecular biology tools, genome editing, and in vivo modeling, and therapeutic studies. Excellent collaborations with academics and industry further expand the scope of our work and fuel new strategies.