This course, which has focused primarily on depression, will be expanded to provide an overview of the methods used in measuring psychosocial and clinical variables, such as depression, stress, social support, anxiety, comorbidity and disease severity. It will also review widely used measures of function and quality of life. Students will learn how to collect high quality data using standardized procedures. In addition, they will learn the basic rules required for creating new measures for variables that are not adequately captured with existing measures. At the conclusion of the course, students will be able to identify the most appropriate measures for their projects.